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ISSN (Print): 2359-4802 | ISSN (Online): 2359-5647

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1 result(s) for: Bruna Eibel

Inflammation markers, microalbuminuria and blood pressure control in primary health care

Marcadores de inflamação, microalbuminúria e controle de pressão arterial em cuidados de saúde primários

Guilherme Brasil Grezzana; Bruna Eibel; Airton Tetelbom Stein; Lúcia Campos Pellanda

Int J Cardiovasc Sci.2016;29(4):295-302 : Original Article


BACKGROUND: Systemic arterial hypertension (SAH) is an important cause of cardiovascular morbidity and mortality. In spite of the effectiveness of the treatment, a high number of patients do not obtain blood pressure (BP) control, a fact that implies the need for investigating the role of other additional factors, such as inflammation markers and microalbuminuria, especially in health care environments.
OBJECTIVES: To evaluate the association between serum fibrinogen levels, ultra-sensitive C-reactive protein (CRP) and microalbuminuria, with blood pressure (BP) averages evaluated by 24-hour ambulatory blood pressure monitoring (ABPM) in hypertensive patients in primary health care setting.
METHODS: A cross-sectional study with hypertensive patients who were seen in primary health care centers was performed. A BP evaluation was carried out by the primary care doctor, and this procedure was followed by a reference test 24-hour ABPM, performed by an independent professional. Moreover, the peripheral blood collect was performed for future biochemical markers analysis.
RESULTS: 143 patients were included. There was a trend for association between the independent variable (altered BP by 24-hour ABPM) and the dependent variable (CRP), there was an association between the values > 3 mg/dL and altered 24-hour ABPM. The prevalence ratio (PR) was of 1.36 (CI 95% 0.90 - 2.06); p=0.18. Regarding microalbuminuria and fibrinogen findings, a 1.03 (CI 95% 0.41 - 2.57) PR was seen; p=1 and 1.19 (CI 95% 0.96 - 1.46) PR; p=0.019, respectively, and both were not significant for altered BP by 24-hour ABPM.
CONCLUSIONS: It is a trend for association between CRP with BP evaluated by 24-hour ABPM in the primary care setting. (Int J Cardiovasc Sci. 2016;29(4):295-302)